[Advances in the mechanism of mesenchymal stem cells in promoting wound healing]
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Updated: Mar 26, 2026

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
Published on: February 17, 2023
Wenjing Zhu1, Haobo Sun1, Guozhong Lyu2
1Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China.
Abstract:
Mesenchymal stem cells possess the ability of self-renewal and multiple differentiation potential, thus exert immunomodulatory effect during tissue repair. Mesenchymal stem cells can stimulate angiogenesis and promote tissue repair through transdifferentiation and secreting a variety of growth factors and cytokines. This review outlines the advances in the mechanism of mesenchymal stem cells in promoting wound healing, including alleviation of inflammatory response, induction of angiogenesis, and promotion of migration of mesenchymal stem cells to the site of tissue injury.
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