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Molecular Pathology of Ovarian Carcinomas
Martin Köbel1, David Huntsman2
1Department of Pathology, University of Calgary and Calgary Laboratory Services, Foothills Medical Centre, 1403 29 ST NW, Calgary, Alberta, Canada T2N 2T9.
Abstract:
This content presents a review of molecular pathology of ovarian cancer. The authors present key molecular features for high-grade and low-grade serous carcinomas, endometrioid carcinomas, clear cell carcinomas, and mucinous carcinomas. Cell lineage, mutation and gene expression, pathway alterations, risk factors, prognostic markers, and treatment targets are discussed.
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