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Updated: Mar 26, 2026
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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
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Parathyroid: The Pathology of Hyperparathyroidism
Virginia A LiVolsi1, Kathleen T Montone1, Zubair N Baloch1
1Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Surgical Pathology Clinics
|February 4, 2016
Summary
This review examines pathologic conditions linked to human hyperparathyroidism, detailing lesions, their origins, and key features. It incorporates immunohistology, cytopathology, and molecular insights for a comprehensive understanding.
Area of Science:
- Endocrinology
- Pathology
Background:
- Hyperparathyroidism is a condition characterized by excessive parathyroid hormone production.
- It can lead to various pathologic entities affecting multiple organ systems.
- Understanding these entities is crucial for diagnosis and management.
Purpose of the Study:
- To provide a comprehensive review of the pathologic entities associated with hyperparathyroidism in humans.
- To discuss the embryology and pathologic features of these lesions.
- To include modern diagnostic techniques and molecular aspects.
Main Methods:
- Literature review focusing on pathologic entities in hyperparathyroidism.
- Inclusion of embryologic and pathologic descriptions.
- Integration of immunohistology, cytopathology, and molecular data.
Main Results:
- Detailed description of various pathologic lesions associated with hyperparathyroidism.
- Explanation of the embryologic development of affected tissues.
- Discussion of characteristic histopathologic findings.
Conclusions:
- Hyperparathyroidism is associated with a spectrum of distinct pathologic entities.
- Comprehensive understanding requires integrating embryology, pathology, and molecular biology.
- Advanced techniques like immunohistology and cytopathology aid in diagnosis.
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