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Related Concept Videos

Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

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Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
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Classification of Epithelial Tissues: Simple Epithelium01:30

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Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
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Classification of Epithelial Tissues: Stratified Epithelium01:29

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Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
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The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
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Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
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Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Epithelioid Lesions.

Andrea T Deyrup1

  • 1Department of Orthopaedic Surgery, University of South Carolina School of Medicine, 701 Grove Road, Greenville, SC 29605, USA; Pathology Consultants of Greenville, 8 Memorial Medical Court, Greenville, SC 29605-4449, USA.

Surgical Pathology Clinics
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Summary
This summary is machine-generated.

Epithelioid soft tissue tumors can mimic carcinoma, posing diagnostic challenges. Accurate classification requires considering these variants and utilizing immunohistochemistry for definitive diagnosis.

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Area of Science:

  • Pathology
  • Oncology
  • Histology

Background:

  • Epithelioid morphology is observed in various mesenchymal tumors.
  • Soft tissue tumors with epithelioid features include vascular lesions, sarcomas, and nerve sheath tumors.

Purpose of the Study:

  • To review epithelioid soft tissue tumors.
  • To highlight diagnostic challenges and the importance of immunohistochemistry.

Main Methods:

  • Literature review of epithelioid soft tissue tumors.
  • Discussion of differential diagnoses and immunohistochemical findings.

Main Results:

  • Epithelioid variants occur in diverse mesenchymal tumors.
  • These tumors can be mistaken for carcinoma.
  • Epithelioid soft tissue tumors often express epithelial antigens.

Conclusions:

  • Consider epithelioid morphology in soft tissue lesions.
  • Immunohistochemistry is crucial for accurate classification of epithelioid soft tissue tumors.