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Thyroid Cancer Epidemiology in Iran: a Time Trend Study
Ali Safavi1, Fereidoun Azizi, Rozita Jafari
1Department of Otolaryngology, Head and Neck Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Thyroid cancer incidence rose in Iran from 2004-2010, mainly due to papillary thyroid cancer. A notable exception was a decrease in pediatric thyroid cancer cases.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Global rise in thyroid cancer necessitates understanding regional trends.
- Investigating temporal patterns in Iranian thyroid cancer incidence is crucial.
Purpose of the Study:
- To analyze thyroid cancer incidence trends in Iran from 2004 to 2010.
- To examine trends by gender, age, and cancer morphology.
Main Methods:
- Utilized the Iran Cancer Data System (ICDS) Registry.
- Analyzed data from 10,913 new thyroid cancer cases (2004-2010).
- Assessed incidence rates across different demographics and morphologies.
Main Results:
- Overall incidence: 2.20 per 100,000 person-years.
- Papillary thyroid cancer was the predominant type (0.29 annual rate).
- Peak incidence at age 45; female-to-male ratio of 2:1.
- Decreased trend in children (<19 years) contrasted with older groups.
Conclusions:
- Thyroid cancer incidence increased overall, driven by papillary histology.
- Age-specific trends showed increases in all groups except those under 19.
- Pediatric thyroid cancer trend was distinct from the general population.
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