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Updated: Mar 26, 2026

Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue
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Published on: June 6, 2016

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Placental Mesenchymal Dysplasia

Ona Marie Faye-Petersen1, Raj P Kapur2

  • 1Pathology, The University of Alabama at Birmingham, 619 19th Street South, NP 3547, Birmingham, AL 35249-7331, USA; Obstetrics and Gynecology, The University of Alabama at Birmingham, 619 19th Street South, NP 3547, Birmingham, AL 35249-7331, USA.

Surgical Pathology Clinics
|February 4, 2016
PubMed

Placental mesenchymal dysplasia is a rare, incompletely understood placental stromal lesion, characterized by placentomegaly and striking ectasia and tortuosity of chorionic plate and stem villous vessels. Its prenatal ultrasonographic and gross pathologic features resemble those of a partial mole, but the fetus is typically normal and the placenta has a diploid, chromosomal complement. We discuss the pathologic features and current understanding of the etiopathogenesis of this condition, the supportive immunohistochemical and confirmatory molecular genetic studies important in its diagnosis, and its implications for pregnancy and infant outcomes.

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