Related Experiment Video
Updated: Mar 26, 2026

08:46
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
6.9K
Fertility Preservation Options for Men and Women With Cancer
Malgorzata E Skaznik-Wikiel1, Sara Babcock Gilbert1, Randall B Meacham2
1Department of Obstetrics and Gynecology, University of Colorado-Denver, Aurora, CO.
Reviews in Urology
|February 4, 2016
Summary
Childhood cancer survivors often face fertility issues due to treatments like chemotherapy and radiotherapy. This article details cancer therapy
Area of Science:
- Oncology
- Reproductive Medicine
- Medical Ethics
Background:
- Childhood cancer survival rates have improved significantly.
- Cancer treatments, including chemotherapy and radiotherapy, can impair fertility.
- Young cancer patients desire information on fertility preservation options.
Purpose of the Study:
- To detail the impact of cancer treatments on male and female reproductive function.
- To outline current and experimental fertility preservation methods for cancer patients.
Main Methods:
- Literature review of studies on cancer treatment effects on fertility.
- Analysis of established and emerging fertility preservation techniques.
Main Results:
- Cancer therapies can lead to long-term or permanent reproductive damage.
- Various fertility preservation options exist, ranging from established to experimental.
Conclusions:
- Informing patients about fertility risks and preservation options is crucial before cancer treatment.
- Further research into novel fertility preservation methods is warranted.
Related Concept Videos
Infertility in Males
678
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
678
Infertility in Females
5.0K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
5.0K
Spermatogenesis
124.6K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
124.6K
Cancer Therapies
10.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.6K
Birth Control Methods
7.2K
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
7.2K
Treatment Resistant Cancers
3.9K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.9K

