Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging the Human Immunological Synapse09:37

Imaging the Human Immunological Synapse

15.4K
This protocol images both the immunological synapse formation and the subsequent polarized secretory traffic towards the immunological synapse. Cellular conjugates were formed between a superantigen-pulsed Raji cell (acting as an antigen-presenting cell) and a Jurkat clone (acting as an effector helper T...
15.4K
Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

10.2K
This protocol describes the use of single chain MHC class I complexes to investigate molecular interactions in human CD8+ T cell activation: generation of engineered antigen presenting cells expressing single chain constructs, culture of human CD8+ T cell clone and T cell activation...
10.2K
A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

15.6K
Biochemical assays with recombinant human MHC II molecules can provide rapid, quantitative insights into immunogenic epitope identification, deletion, or design.  Here, a peptide-MHC II binding assay scaled to 384-well plates is described. This cost effective format should prove useful in the fields of protein deimmunization and vaccine design and...
15.6K
Supported Planar Bilayers for the Formation of Study of Immunological Synapses and Kinapse12:24

Supported Planar Bilayers for the Formation of Study of Immunological Synapses and Kinapse

13.1K
Supported planar bilayers are powerful tools that can be used to model the molecular interactions in an immunological synapse. Here, we show methods for anchoring cell adhesion proteins known to modulate synapse formation to the upper leaflet of the lipid bilyer and visualize synapse formation using TIRF microscopy.
13.1K
Immunological Synapse Formation Between Helper T Cells and Antigen-Presenting Cells03:31

Immunological Synapse Formation Between Helper T Cells and Antigen-Presenting Cells

1.1K
This video demonstrates the in vitro study of immunological synapse formation between an antigen-presenting cell and helper T lymphocytes using a fluorescence microscope. T cell receptors of helper T lymphocytes interact with an antigen-MHC-II complex in antigen-presenting cells and form immunological synapses, followed by secretory vesicle movements toward the synapse, which is visualized by fluorescent...
1.1K
Immunological Memory01:23

Immunological Memory

15.1K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
15.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Relationship between obsessive compulsive symptomatology and severity of psychotic symptoms in schizophrenia: Meta-analysis and meta-regression analysis.

Schizophrenia research·2022
Same author

Reducing milking frequency in early lactation improved the energy status but reduced milk yield during the whole lactation of primiparous Holstein cows consuming a total mixed ration and pasture.

Journal of dairy science·2019
Same author

Anxiety and depression in women with breast cancer: Social and clinical determinants and influence of the social network and social support (DAMA cohort).

Cancer epidemiology·2018
Same author

Probiotic properties of native Lactobacillus spp. strains for dairy calves.

Beneficial microbes·2018
Same author

pVAX14DNA-mediated add-on immunotherapy combined with arsenic trioxide and all-trans retinoic acid targeted therapy effectively increases the survival of acute promyelocytic leukemia mice.

Blood cancer journal·2015
Same author

Lithium chloride antileukemic activity in acute promyelocytic leukemia is GSK-3 and MEK/ERK dependent.

Leukemia·2015
Same journal

[Lentivirus expression at the moment of lambing modifies the leukocyte number in the milk of multiparous ewes].

Annales de recherches veterinaires. Annals of veterinary research·1992
Same journal

Conjunctival vaccination of pregnant ewes and goats with Brucella melitensis Rev 1 vaccine: safety and serological responses.

Annales de recherches veterinaires. Annals of veterinary research·1992
Same journal

[Actinomyces pyogenes: conventional and Api system bacteriologic study of 103 strains isolated from ruminants].

Annales de recherches veterinaires. Annals of veterinary research·1992
Same journal

Influence of the stage of pregnancy on gentamicin disposition in the ewe.

Annales de recherches veterinaires. Annals of veterinary research·1992
Same journal

Effect of vitamin E supplementation and of health status of mammary gland on immunoglobulin concentration in milk of dairy cows.

Annales de recherches veterinaires. Annals of veterinary research·1992
Same journal

[Content of nitrate in milk. Relationship with its concentration in the water supply for livestock].

Annales de recherches veterinaires. Annals of veterinary research·1992
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

10.2K

[Non-immunologic functions associated with the MHC]

M Pla1

  • 1INSERM, Immunogénétique de la souris, U93, Hôpital Saint-Louis, Paris, France.

Annales De Recherches Veterinaires. Annals of Veterinary Research
|January 1, 1989
PubMed
Summary

No abstract available in PubMed .

More Related Videos

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

15.6K
Immunological Synapse Formation Between Helper T Cells and Antigen-Presenting Cells
03:31

Immunological Synapse Formation Between Helper T Cells and Antigen-Presenting Cells

1.1K

Related Experiment Videos

Last Updated: Jan 19, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
12:09

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

10.2K
A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

15.6K
Immunological Synapse Formation Between Helper T Cells and Antigen-Presenting Cells
03:31

Immunological Synapse Formation Between Helper T Cells and Antigen-Presenting Cells

1.1K