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Ablation techniques for primary and metastatic liver tumors
Michael J Ryan1, Jonathon Willatt1, Bill S Majdalany1
1Michael J Ryan, Jonathon Willatt, Bill S Majdalany, Suzanne Chong, Julie A Ruma, Amit Pandya, Department of Radiology, University of Michigan, Ann Arbor, MI 48109, United States.
World Journal of Hepatology
|February 4, 2016
Summary
Ablative therapies offer safe and effective treatments for liver tumors in non-surgical patients. This review covers techniques, complications, and outcomes for radiofrequency ablation, microwave ablation, cryoablation, and irreversible electroporation.
Area of Science:
- Oncology
- Interventional Radiology
- Surgical Oncology
Background:
- Primary and secondary liver tumors pose significant treatment challenges.
- Surgical resection is not feasible for all patients.
- Minimally invasive therapies are crucial for unresectable liver malignancies.
Purpose of the Study:
- To review current literature on ablative treatment methods for liver tumors.
- To describe techniques, complications, and results of various ablation modalities.
- To provide an overview for clinicians managing patients with unresectable liver tumors.
Main Methods:
- Literature review of radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation, and irreversible electroporation (IRE).
- Analysis of reported techniques, procedural parameters, and patient selection criteria.
- Compilation of data on efficacy, safety, and complication rates.
Main Results:
- Ablative techniques demonstrate safety and efficacy in treating primary and secondary liver tumors.
- Radiofrequency ablation and microwave ablation are widely used with established outcomes.
- Cryoablation and irreversible electroporation offer alternative options with specific indications and results.
Conclusions:
- Ablative therapies are valuable tools for managing unresectable liver tumors.
- The choice of ablation modality depends on tumor characteristics and patient factors.
- Continued research is needed to optimize techniques and expand applications.
