Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

25
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
25

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuroprotective Agents for Photoreceptor Rescue Following Experimental Retinal Detachment in Rodents: A Systematic Review.

Investigative ophthalmology & visual science·2026
Same author

Adherence to the Mediterranean Diet by Greek Patients With Glaucoma: An Observational Study.

Cureus·2026
Same author

An ancestry-enriched HNF4A variant and GP2 reveal distinct mechanisms of type 2 diabetes in exome-wide study of 13,674 cases and 41,024 controls.

medRxiv : the preprint server for health sciences·2026
Same author

The Biobank Rare Variant consortium powers the discovery of rare genetic associations through global collaboration.

medRxiv : the preprint server for health sciences·2026
Same author

Clinician-Centered Evaluation Framework for Explainable AI Heatmaps in OCT-Based Retinal Disease Classification.

Journal of imaging·2026
Same author

Humanistic and Economic Burden of Patients With Keratoconus.

Cureus·2026

Related Experiment Video

Updated: Mar 26, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

13.4K

Posttraumatic Sphingomonas paucimobilis Endophthalmitis.

Konstantinos Droutsas1, Georgios Kalantzis1, Chrysanthos Symeonidis2

  • 11st Department of Ophthalmology, University of Athens, General Hospital "G. Gennimatas", Mesogeion Avenue 158, 156 69 Athens, Greece.

Case Reports in Ophthalmological Medicine
|February 4, 2016
PubMed
Summary

This study reports the first case of Sphingomonas paucimobilis endophthalmitis after a penetrating eye injury with a retained foreign body. Prompt treatment led to a good healing response, though visual acuity remained low due to retinal complications.

More Related Videos

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

2.0K
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.3K

Related Experiment Videos

Last Updated: Mar 26, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

13.4K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

2.0K
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.3K

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Penetrating globe injuries can lead to severe intraocular infections.
  • Endophthalmitis is a serious complication that can result in vision loss.
  • Sphingomonas paucimobilis is a rare cause of endophthalmitis, particularly after ocular trauma.

Purpose of the Study:

  • To present a rare case of Sphingomonas paucimobilis endophthalmitis following a penetrating globe injury.
  • To highlight the diagnostic and therapeutic challenges associated with this condition.
  • To contribute to the literature on microbial causes of endophthalmitis.

Main Methods:

  • Case presentation of a 30-year-old male with penetrating left eye injury and retained metallic foreign body.
  • Clinical examination, ultrasonography, and orbital CT scan for diagnosis.
  • Pars-plana vitrectomy with foreign body removal and vitreous sampling for microbial analysis.
  • Ceftazidime sensitivity testing for the identified pathogen.

Main Results:

  • Sphingomonas paucimobilis was identified as the causative agent of endophthalmitis.
  • The organism was sensitive to ceftazidime.
  • Surgical intervention and antibiotic therapy resulted in a favorable initial healing response.
  • Despite treatment, long-term retinal complications led to reduced visual acuity.

Conclusions:

  • Sphingomonas paucimobilis can cause severe endophthalmitis following penetrating ocular trauma.
  • Early diagnosis and appropriate surgical and medical management are crucial.
  • While antibiotic sensitivity can lead to good healing, visual outcomes may be compromised by secondary complications.