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Disseminated cutaneous infection due to Mycobacterium chelonae following hematopoietic stem cell transplantation

C Ferry1, A Saussine2, J D Bouaziz2

  • 1Service hematologie greffe, AP-HP, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France.

Idcases
|February 4, 2016
PubMed

Insights

Disseminated cutaneous Mycobacterium chelonae infections were observed in two patients following hematopoietic stem cell transplantation (HSCT). This highlights a rare but serious complication after this procedure.

Area of Science:

  • Infectious Diseases
  • Hematology
  • Transplantation Immunology

Background:

  • Hematopoietic stem cell transplantation (HSCT) is a complex procedure that can lead to various complications.
  • Disseminated cutaneous infections are a known risk in immunocompromised patients.

Purpose of the Study:

  • To report and characterize two cases of disseminated cutaneous Mycobacterium chelonae infection post-HSCT.
  • To raise awareness of this rare adverse event in HSCT recipients.

Main Methods:

  • Case report of two patients who developed disseminated cutaneous Mycobacterium chelonae.
  • Review of clinical presentation, diagnostic methods, and treatment outcomes.

Main Results:

  • Two patients developed widespread skin lesions caused by Mycobacterium chelonae after HSCT.
  • Infections presented with diverse cutaneous manifestations.

Conclusions:

  • Disseminated cutaneous Mycobacterium chelonae is a rare but significant complication after HSCT.
  • Prompt diagnosis and appropriate antimicrobial therapy are crucial for managing these infections.

Keywords:
Chronic graft versus host diseaseHematopoietic stem cell transplantationMycobacterium chelonae

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