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Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
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Pseudomonas bacteremia as an initial presentation of SLE
Veenu Gill1, Jatinbhai Patel2, Sanjana Koshy3
1Mount Sinai Beth Israel, Milton and Carroll Petrie Division, First Avenue at 16th Street, Baird Hall, 19th Floor, New York, NY 10003, United States.
Idcases
|February 4, 2016
Summary
Infections can trigger lupus relapses or lead to diagnosis. This case highlights Pseudomonas aeruginosa bacteremia in a young patient newly diagnosed with systemic lupus erythematosus (SLE), emphasizing the gut-vasculitis-sepsis connection.
Area of Science:
- Infectious Diseases
- Rheumatology
- Gastroenterology
Background:
- Infections are frequently linked to systemic lupus erythematosus (SLE) relapses.
- Infections can also initiate the diagnostic process for SLE.
- Intestinal vasculitis is a known complication in SLE patients with abdominal pain.
Purpose of the Study:
- To report a case of new-onset SLE diagnosed in a young patient presenting with Pseudomonas aeruginosa bacteremia.
- To illustrate the potential link between gastrointestinal pathology, bacteremia, and SLE diagnosis.
- To highlight the role of intestinal vasculitis in SLE-related sepsis.
Main Methods:
- Case report of a young patient with Pseudomonas aeruginosa bacteremia.
- Review of literature linking infections, SLE, and gastrointestinal complications.
- Clinical and microbiological diagnostic workup.
Main Results:
- A young patient presented with Pseudomonas aeruginosa bacteremia.
- The patient was diagnosed with new-onset systemic lupus erythematosus (SLE).
- The case underscores the potential for bacteremia originating from the gastrointestinal tract due to vasculitis in SLE.
Conclusions:
- Pseudomonas aeruginosa bacteremia can be an early manifestation of systemic lupus erythematosus (SLE).
- Intestinal vasculitis in SLE can lead to gut ischemia, pathogen translocation, and sepsis.
- Infectious presentations should prompt consideration of underlying autoimmune diseases like SLE.
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