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BOWEL PREPARATION BEFORE COLONOSCOPY FOR CHILDREN: comparison of efficacy of three different methods
Seyed Mohsen Dehghani1, Hazhir Javaherizadeh1, Mahmood Haghighat1
1Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Insights
Comparing three 1-day bowel preparation methods for pediatric colonoscopy, polyethylene glycol (PEG) with bisacodyl suppositories showed slightly better results than PEG with saline enema. However, no significant differences in overall bowel preparation scores were found among the regimens.
Area of Science:
- Gastroenterology
- Pediatric Endoscopy
- Clinical Trial Methodology
Background:
- Colonoscopy is a crucial procedure requiring adequate bowel preparation.
- Polyethylene glycol (PEG) is a widely used agent for bowel cleansing.
- Optimizing 1-day preparation regimens is essential for pediatric colonoscopy efficacy.
Purpose of the Study:
- To compare the efficacy of three distinct 1-day bowel preparation methods for pediatric colonoscopy.
- To evaluate polyethylene glycol (PEG) alone, PEG with bisacodyl suppositories, and PEG with normal saline enema.
Main Methods:
- Inclusion of children aged 2-21 years undergoing colonoscopy.
- Exclusion of patients with prior surgery or incomplete protocol adherence.
- Assessment of bowel preparation using the Boston Bowel Preparation Score (BPPS).
Main Results:
- Acceptable bowel preparation was achieved in 85.71% (PEG), 94.73% (PEG + bisacodyl), and 82.35% (PEG + saline enema) of cases.
- PEG with bisacodyl demonstrated superior preparation in the first colon segment (P=0.05).
- Higher BPPS scores in the second and third segments for PEG + bisacodyl were not statistically significant.
Conclusions:
- No statistically significant difference in overall bowel preparation scores among the three 1-day regimens.
- The PEG with normal saline enema group showed the lowest preparation scores.
- Further research may be needed to determine optimal pediatric bowel preparation protocols.
Background:
Colonoscopy is an important diagnostic and therapeutic procedure. Adequate bowel preparation is mandatory. Several regimens were discussed in the literature. Among the drugs which has recently used, polyethylene glycol is one of the most popular agents.
Objectives:
The aim of this study was to compare efficacy of three different methods for 1 day preparation before colonoscopy.
Methods:
This study included children with the range of ages (2-21) who had an indication of colonoscopy. Exclusion criteria were based on the history of previous surgery, parental disagreement, and patients who did not use preparation protocol. Three methods for bowel preparation were studied: 1- Polyethylene glycol only; 2- Polyethylene glycol and bisacodyl suppositories; 3- Polyethylene glycol plus normal saline enema. Boston Bowel Preparation Score was used for evaluation of preparation. SPSS version 16.0 (Chicago, IL, USA) were used for data analysis.
Results:
In this study 83 cases completed the bowel preparation completely. Acceptable bowel preparation was seen in 24 (85.71%), 36 (94.73%), and 14 (82.35%) of cases in PEG, PEG + bisacodyl, and PEG + normal saline enema groups respectively. PEG + bisacodyl suppositories was more effective than PEG + normal saline for the preparation of the first segment ( P=0.05). For second and third segment of colon, BPPS score was higher in PEG + bisacodyl suppositories compared to other regimens, but this difference was not statistically significant.
Conclusion:
There was no significant difference between 1 day colonoscopy regimens in terms of bowel preparation score. Lowest score was seen in PEG + enema group compared to other group.
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