BOWEL PREPARATION BEFORE COLONOSCOPY FOR CHILDREN: comparison of efficacy of three different methods

Seyed Mohsen Dehghani1, Hazhir Javaherizadeh1, Mahmood Haghighat1

  • 1Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Insights

Comparing three 1-day bowel preparation methods for pediatric colonoscopy, polyethylene glycol (PEG) with bisacodyl suppositories showed slightly better results than PEG with saline enema. However, no significant differences in overall bowel preparation scores were found among the regimens.

Area of Science:

  • Gastroenterology
  • Pediatric Endoscopy
  • Clinical Trial Methodology

Background:

  • Colonoscopy is a crucial procedure requiring adequate bowel preparation.
  • Polyethylene glycol (PEG) is a widely used agent for bowel cleansing.
  • Optimizing 1-day preparation regimens is essential for pediatric colonoscopy efficacy.

Purpose of the Study:

  • To compare the efficacy of three distinct 1-day bowel preparation methods for pediatric colonoscopy.
  • To evaluate polyethylene glycol (PEG) alone, PEG with bisacodyl suppositories, and PEG with normal saline enema.

Main Methods:

  • Inclusion of children aged 2-21 years undergoing colonoscopy.
  • Exclusion of patients with prior surgery or incomplete protocol adherence.
  • Assessment of bowel preparation using the Boston Bowel Preparation Score (BPPS).

Main Results:

  • Acceptable bowel preparation was achieved in 85.71% (PEG), 94.73% (PEG + bisacodyl), and 82.35% (PEG + saline enema) of cases.
  • PEG with bisacodyl demonstrated superior preparation in the first colon segment (P=0.05).
  • Higher BPPS scores in the second and third segments for PEG + bisacodyl were not statistically significant.

Conclusions:

  • No statistically significant difference in overall bowel preparation scores among the three 1-day regimens.
  • The PEG with normal saline enema group showed the lowest preparation scores.
  • Further research may be needed to determine optimal pediatric bowel preparation protocols.
Abstract

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