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Updated: Mar 26, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
Published on: October 31, 2010
Multifaceted intervention including education, rounding checklist implementation, cost feedback, and financial
Peter M Yarbrough1,2, Polina V Kukhareva3, Devin Horton1
1Department of Internal Medicine, Division of General Internal Medicine, University of Utah Medical Center, Salt Lake City, Utah.
Background:
Inappropriate laboratory testing is a contributor to waste in healthcare.
Objective:
To evaluate the impact of a multifaceted laboratory reduction intervention on laboratory costs.
Design:
A retrospective, controlled, interrupted time series (ITS) study.
Setting:
University of Utah Health Care, a 500-bed academic medical center in Salt Lake City, Utah.
Population:
All patients 18 years or older admitted to the hospital to a service other than obstetrics, rehabilitation, or psychiatry.
Intervention:
Multifaceted quality-improvement initiative in a hospitalist service including education, process change, cost feedback, and financial incentive.
Measurements:
Primary outcomes of lab cost per day and per visit. Secondary outcomes of number of basic metabolic panel (BMP), comprehensive metabolic panel (CMP), complete blood count (CBC), and prothrombin time/international normalized ratio tests per day; length of stay (LOS); and 30-day readmissions.
Results:
A total of 6310 hospitalist patient visits (intervention group) were compared to 25,586 nonhospitalist visits (control group). Among the intervention group, the unadjusted mean cost per day was reduced from $138 before the intervention to $123 after the intervention (P < 0.001), and the unadjusted mean cost per visit decreased from $618 to $558 (P = 0.005). The ITS analysis showed significant reductions in cost per day, cost per visit, and the number of BMP, CMP, and CBC tests per day (P = 0.034, 0.02, <0.001, 0.004, and <0.001). LOS was unchanged and 30-day readmissions decreased in the intervention group.
Conclusion:
A multifaceted approach to laboratory reduction demonstrated a significant reduction in laboratory cost per day and per visit, as well as common tests per day at a major academic medical center. Journal of Hospital Medicine 2016;11:348-354. © 2016 Society of Hospital Medicine.
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