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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
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Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy

Susanne J van Veluw1, Geert Jan Biessels2, Catharina J M Klijn2

  • 1From the Department of Neurology, Brain Center Rudolf Magnus (S.J.v.V., G.J.B., C.J.M.K.), and the Department of Pathology (A.J.M.R.), University Medical Center Utrecht; Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Center for Neuroscience (C.J.M.K.), Radboud University Medical Center, Nijmegen; and Department of Pathology (A.J.M.R.), VU Medical Center, Amsterdam, the Netherlands. s.j.veluw-2@umcutrecht.nl.

Neurology
|February 5, 2016
PubMed
Abstract

Insights

Postmortem MRI revealed diverse causes for microbleeds in severe cerebral amyloid angiopathy (CAA) and Alzheimer disease, including recent hemorrhages, vascular damage, and old hemorrhages with chronic ischemic injury.

Area of Science:

  • Neuropathology
  • Neuroimaging
  • Cerebrovascular Diseases

Background:

  • Severe cerebral amyloid angiopathy (CAA) and Alzheimer pathology are associated with microhemorrhages.
  • High-resolution 7T postmortem MRI can detect microbleeds.

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