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Updated: Aug 10, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
[Chondrosarcoma: clinical and radiological analysis of 206 cases]
Abstract:
206 cases of chondrosarcoma including central type 159 cases and peripheral type 47 all proved by surgery and pathology were analysed. The important aggressive X-ray signs of central (primary) chondrosarcoma include: Infiltrating, notching and scalloping of the endosteal cortical surface; irregular and ill-defined margin between tumor and bone, transition zone widened or 'moth-eaten' in appearance; soft tissue tumor mass may grow eccentrically or concentrically around the bone; various patterns of calcification within the tumor and localized laminated periosteal reaction. The radiologic features of the secondary peripheral chondrosarcoma are: fuzzy and indistinct surface in the region of the cartilaginous cap which becomes irregular and thickened (more than 1 cm); formation of a soft tissue mass containing faint flocculent or ring-like calcifications; the "bursting" and scattering of old calcifications in the depth of the cartilage cap and destruction of adjacent bone.
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