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Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
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Tuberculous epididymo-orchitis masquerading as acute scrotum
Ned Kinnear1, Ivan Hoh2, Pedro Campillo2
1Department of General Surgery, Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia.
BMJ Case Reports
|February 6, 2016
Summary
Tuberculosis can manifest as testicular abscess, even in young refugees. Early recognition and targeted treatment are crucial for favorable outcomes in such cases.
Area of Science:
- Urology
- Infectious Diseases
- Public Health
Background:
- Testicular pain in young individuals often suggests epididymo-orchitis.
- Refugees from endemic areas may present with atypical infections.
- Delayed diagnosis of tuberculosis can lead to severe complications.
Observation:
- An 18-year-old Afghan refugee presented with severe testicular pain, initially diagnosed as epididymo-orchitis.
- He later developed a testicular abscess, confirmed as tuberculous infection.
- The patient had risk factors for tuberculosis but received a delayed diagnosis.
Findings:
- Surgical drainage of the abscess facilitated laboratory confirmation of tuberculous infection.
- A 9-month regimen of standard anti-tuberculosis drugs (isoniazid, rifampicin, ethambutol, pyrazinamide) with vitamin B6 resulted in a good clinical response.
- This case highlights the importance of considering tuberculosis in the differential diagnosis of testicular abscesses, especially in high-risk populations.
Implications:
- Clinicians should maintain a high index of suspicion for tuberculosis in patients with testicular abscesses, particularly those with relevant epidemiological risk factors.
- Prompt diagnosis and appropriate anti-tuberculosis therapy are essential for managing this condition and preventing long-term sequelae.
- Public health strategies should address the screening and management of tuberculosis in refugee populations to mitigate risks of delayed diagnosis and treatment.
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