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Updated: Mar 26, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Sleep quality changes in chronically depressed patients treated with Mindfulness-based Cognitive Therapy or the
Preetam J Schramm1, Ingo Zobel2, Kathrin Mönch3
1REM Sleep Medicine, Boulder, CO, USA.
Objective:
To capture any sleep quality changes associated with group psychotherapy.
Patients/Methods:
Physician-referred, chronically depressed patients (n = 25) were randomized to either eight group sessions of Mindfulness-based Cognitive Therapy (MBCT, n = 9) plus Treatment As Usual (TAU), or the Cognitive Behavioral Analysis System of Psychotherapy (CBASP, n = 8) plus TAU, or to TAU only (control group, n = 8). Participants recorded their sleep at home. The primary outcome variables were: stable and unstable sleep, which were assessed using cardiopulmonary coupling (CPC) analysis, and estimated total sleep and wake time (minutes). Cardiopulmonary coupling measures heart rate variability and the electrocardiogram's R-wave amplitude fluctuations associated with respiration.
Results:
By post-treatment night 6, the CBASP group had more stable sleep (p= 0.044) and less wake (p = 0.004) compared with TAU, and less wake vs MBCT (p = 0.039).
Conclusion:
The CBASP group psychotherapy treatment improved sleep quality compared with Treatment As Usual.
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