[Phenotypic analysis and gene expression of inflammatory reaction forms of the monocyte/macrophage system]

The phenotypic heterogeneity of the monocyte/macrophage system is mirrored by the various inflammatory reactions of this cell system. Using monoclonal antibodies functional subpopulations of the monocyte/macrophage system can be observed, though the pathophysiological processes of the various inflammatory reactions still remain mostly unclear. By analysing phenotypic properties and gene expression in cells of the bronchoalveolar lavage it will be shown that the activity and the underlying pathophysiologic mechanisms of reactive processes can be defined.