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Disentangling the associations between parental BMI and offspring body composition using the four-component model
Delan Devakumar1, Carlos Grijalva-Eternod1, Mario Cortina-Borja2
1UCL Institute for Global Health, London, WC1N 1EH, United Kingdom.
Summary
Maternal body mass index (BMI) significantly impacts offspring body composition, including fat and lean mass. Paternal BMI is associated with sons body composition but not daughters.
Area of Science:
- Human Biology
- Anthropometry
- Genetics
Background:
- Parental body mass index (BMI) is a potential determinant of offspring body composition.
- Understanding intergenerational influences on body composition is crucial for public health.
Purpose of the Study:
- To investigate the association between parental BMI and offspring body composition.
- To examine sex-specific differences in these intergenerational associations.
Main Methods:
- Cross-sectional study of 511 parent-offspring trios.
- Offspring aged 5-21 years; parental BMI by recall.
- Offspring body composition (fat mass index, lean mass index) assessed using the four-component model.
Main Results:
- Positive associations found between parental BMI and offspring BMI, fat mass index (FMI), and lean mass index (LMI).
- Maternal BMI associated with BMI, FMI, and LMI z-scores in both sons and daughters.
- Paternal BMI associated with sons' BMI, FMI, and LMI z-scores, but not daughters'.
Conclusions:
- Parental BMI influences offspring body composition, with variable associations.
- Maternal BMI shows significant associations with child's body composition.
- Paternal BMI associations differ by sex, primarily impacting sons.
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