[Approach and Registry of Anaphylaxis in Portugal]

Area of Science:

• Allergy and Immunology
• Emergency Medicine
• Public Health

Background:

• Anaphylaxis incidence is increasing, particularly in children, posing a significant medical emergency.
• Effective anaphylaxis management hinges on timely and appropriate interventions.
• Biphasic reactions necessitate extended clinical observation post-acute event.

Purpose of the Study:

• To present updated Portuguese guidelines for anaphylaxis diagnosis and treatment.
• To standardize and enhance the clinical approach to anaphylaxis in Portugal.
• To promote the utilization of the Portuguese Catalogue of Allergies and other Adverse Reactions (CPARA) for data sharing.

Main Methods:

• Review and synthesis of the latest Portuguese clinical guidelines for anaphylaxis.
• Emphasis on intramuscular epinephrine as the primary treatment, with weight- and age-based dosing.
• Recommendation for epinephrine auto-injector prescription and Immunoallergy consultation referrals.

Main Results:

• Intramuscular epinephrine is the recommended first-line treatment for anaphylaxis.
• Post-treatment surveillance for 6-24 hours is advised due to potential biphasic reactions.
• Referral to Immunoallergy and prescription of epinephrine auto-injectors are key management strategies.

Conclusions:

• Adherence to updated guidelines can lead to more effective and uniform anaphylaxis care.
• The CPARA database is a vital tool for tracking and sharing anaphylaxis information within the health system.
• Proactive management, including early intervention and risk reduction strategies, is essential for improving patient outcomes.