[Association between sleep duration and stroke in adults].

Area of Science:

• Epidemiology
• Neurology
• Sleep Medicine

Background:

• Stroke is a leading cause of death and disability worldwide.
• Sleep duration is a modifiable lifestyle factor with potential implications for cerebrovascular health.

Purpose of the Study:

• To investigate the association between sleep duration and the risk of stroke in a large adult cohort.
• To examine the impact of both short and long sleep durations on stroke incidence.

Main Methods:

• Analysis of baseline data from 57,704 adults aged 30-79 years in the China Kadoorie Biobank (CKB) study.
• Use of multiple logistic regression to assess the association between sleep duration and stroke, adjusting for confounders.
• Exploration of the relationship between frequent sleep snoring and stroke risk.

Main Results:

• A U-shaped distribution was observed between sleep duration and stroke prevalence.
• Long sleep duration (≥ 10 hours/day) was significantly associated with an increased risk of stroke in both males (OR=2.11) and females (OR=2.13).
• No significant association was found between short sleep duration (≤ 6 hours/day) and stroke. Frequent sleep snoring was linked to higher stroke risk in females (OR=1.63).

Conclusions:

• Longer sleep duration is a risk factor for stroke in both genders.
• Frequent sleep snoring is an independent risk factor for stroke, particularly in females.
• These findings highlight the importance of maintaining optimal sleep duration for cerebrovascular health.