Coronary arteries anomalous aortic origin on a computed tomography angiography population: prevalence,
José Amado1, Mónica Carvalho2, Wilson Ferreira2
1Cardiology Department, Serviço de Cardiologia, Centro Hospitalar do Algarve, R. Leão Penedo, 8000-386, Faro, Portugal. pina_amado@hotmail.com.
Insights
Anomalous aortic origin of coronary arteries (AAOCA) is a rare condition. This study found AAOCA prevalence of 1.5% in adults undergoing CT angiography, with no increased middle-term cardiac event risk compared to controls.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Anomalous aortic origin of coronary arteries (AAOCA) is a significant cause of sudden cardiac death in young individuals.
- Understanding the prevalence and clinical impact of AAOCA is crucial for risk stratification.
Purpose of the Study:
- To determine the prevalence and anatomical characteristics of AAOCA in a population undergoing computed tomography angiography (CTA).
- To evaluate the clinical prognosis of patients with AAOCA at mid-term follow-up.
Main Methods:
- Retrospective analysis of 3539 CTAs to identify AAOCA cases.
- Comparison of AAOCA patients with an age- and gender-matched control group.
- Telephone follow-up to assess cardiac events over a mean of 45.9 months.
Main Results:
- AAOCA prevalence was 1.5% (53 cases).
- Most common anomalies included right coronary artery origin from the left sinus and left circumflex artery from the right sinus.
- No significant difference in cardiac events or cardiovascular deaths between AAOCA and control groups.
Conclusions:
- AAOCA is not associated with a worse mid-term prognosis in an adult population referred for CTA.
- Interarterial course of anomalous coronary arteries did not correlate with increased cardiac events.
Abstract:
Anomalous aortic origin of coronary arteries (AAOCA) is one of the most frequent causes of cardiovascular sudden death among the young population. We aimed to determine the prevalence and anatomic characteristics of AAOCA in a population referred to computed tomography angiography (CTA) and to describe the clinical prognosis of these findings at middle term follow-up. From a total of 3539 CTA, 53 were found to have AAOCA. This population was compared to an age and gender matched control group (n = 106) from the same CTA list. A telephone follow-up to determine cardiac events was conducted, with a mean follow-up of 45.9 ± 28.2 months. Prevalence of AAOCA was 1.5 %. The most common AAOCA was an origin of the right coronary artery (RCA) from the left coronary sinus, followed by an origin of the left circumflex artery (LCX) arising from the right coronary sinus. All patients with an anomalous origin of the RCA had an interarterial course. Four additional patients were found to have an interarterial course: 1 with an anomalous origin of LCX and 3 with an anomalous origin of the left main coronary artery (LMCA). At follow-up there were 33 (21.2 %) cardiac events, 9 (17.6 %) on the AAOCA group and 24 (22.9 %) on the control group (p = 0.46). Cardiac events and cardiovascular deaths were not related to any particular AAOCA or to interarterial courses. Among an adult population referred to CTA, AAOCA were not related with worse middle term prognosis when compared to an age- and gender- matched population.
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