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Primary care clinician antibiotic prescribing decisions in consultations for children with RTIs: a qualitative
Jeremy Horwood1, Christie Cabral1, Alastair D Hay1
1Centre for Academic Primary Care, NIHR School of Primary Care Research, School of Social and Community Medicine.
Insights
Healthcare professionals often prescribe antibiotics for children with respiratory tract infections (RTIs) due to uncertainty about illness progression. More training and evidence are needed to guide antibiotic decisions for pediatric RTIs.
Area of Science:
- Pediatric Medicine
- Infectious Diseases
- General Practice
Background:
- Respiratory tract infections (RTIs) are a significant challenge in pediatric primary care.
- Uncertainty in diagnosis and prognosis contributes to antibiotic overuse, leading to medicalization and bacterial resistance.
Purpose of the Study:
- To investigate diagnostic and antibiotic prescribing decisions made by healthcare professionals (HCPs) for children with RTIs.
- To understand the factors influencing these decisions in primary care settings.
Main Methods:
- Semi-structured interviews were conducted with 22 general practitioners (GPs) and six nurses.
- Thematic analysis was used to analyze transcribed interview data from diverse socioeconomic areas.
Main Results:
- HCPs utilized a dual diagnostic process (rapid assessment followed by deductive reasoning).
- Prognostic uncertainty, especially for intermediate severity cases, frequently led to antibiotic prescribing to avoid perceived risks of deterioration.
- Non-clinical factors and a perceived need for more pediatric training influenced prescribing decisions.
Conclusions:
- Prognostic uncertainty is a key driver of antibiotic prescribing for pediatric RTIs.
- Enhanced training in recognizing severe RTIs and evidence to predict illness deterioration could improve antibiotic stewardship.
- Better identification of children who will and will not benefit from antibiotics is crucial.
Background:
Respiratory tract infections (RTIs) are a major primary care challenge in children because they are common and costly, there is uncertainty regarding their diagnosis, prognosis, and management, and the overuse of antibiotics leads to illness medicalisation and bacterial resistance.
Aim:
To investigate healthcare professional (HCP) diagnostic and antibiotic prescribing decisions for children with RTIs.
Design And Setting:
Semi-structured interviews conducted with 22 GPs and six nurses. HCPs were recruited from six general practices and one walk-in centre, serving a mix of deprived and affluent areas.
Method:
Interviews were audiorecorded, transcribed, imported into NVivo 9, and analysed thematically.
Results:
HCPs varied in the symptom and clinical examination findings used to identify children they thought might benefit from antibiotics. Their diagnostic reasoning and assessment of perceived clinical need for antibiotics used a dual process, combining an initial rapid assessment with subsequent detailed deductive reasoning. HCPs reported confidence diagnosing and managing most minor and severe RTIs. However, residual prognostic uncertainty, particularly for the intermediate illness severity group, frequently led to antibiotic prescribing to mitigate the perceived risk of subsequent illness deterioration. Some HCPs perceived a need for more paediatrics training to aid treatment decisions. The study also identified a number of non-clinical factors influencing prescribing.
Conclusion:
Prognostic uncertainty remains an important driver of HCPs' antibiotic prescribing. Experience and training in recognising severe RTIs, together with more evidence to help HCPs identify the children at risk of future illness deterioration, may support HCPs' identification of the children most and least likely to benefit from antibiotics.
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