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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Stroke and Heart Failure: Clinical Features, Access to Care, and Outcomes

Jitphapa Pongmoragot1, Douglas S Lee2, Tai Hwan Park3

  • 1Stroke Outcomes Research Center, Division of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|February 9, 2016
PubMed

Insights

Heart failure (HF) affects 9.1% of acute ischemic stroke (AIS) patients, increasing their risk of death and disability. This study highlights HF as an independent predictor of adverse outcomes following stroke.

Area of Science:

  • Cardiology
  • Neurology
  • Stroke Medicine

Background:

  • Limited data exists on the interplay between acute ischemic stroke (AIS) and heart failure (HF).
  • Understanding this relationship is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the clinical characteristics, predisposing factors, and outcomes of patients experiencing AIS with co-existing HF.
  • To identify HF as a potential predictor of adverse events in AIS patients.

Main Methods:

  • A cohort of 12,396 AIS patients was analyzed from the Registry of the Canadian Stroke Network.
  • Heart failure (HF) was defined by pre-existing HF or pulmonary edema on arrival.
  • Primary outcome was death or disability at discharge (modified Rankin Scale score >3); secondary outcomes included mortality, disposition, and readmissions.

Main Results:

  • Heart failure (HF) was present in 9.1% of AIS patients.
  • HF was significantly associated with increased risk of death at 30 days, 1 year, and disability at discharge.
  • Multivariable analysis confirmed HF as an independent predictor of death, disability, and 30-day hospital readmissions.

Conclusions:

  • Heart failure (HF) is a significant comorbidity in 9.1% of acute ischemic stroke (AIS) patients.
  • HF independently predicts worse outcomes, including death, disability, and readmissions, in the 30 days following stroke.
Abstract

Keywords:
Strokeheart failureoutcomesquality of care

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