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Updated: Mar 26, 2026
Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
Factors associated with biopsy site identification, postponement of surgery, and patient confidence in a dermatologic
Junqian Zhang1, Alex Rosen1, Lauren Orenstein2
1Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Background:
Biopsy site identification is critical to avoid wrong-site surgery and may impact patient-centered outcomes.
Objective:
We sought to evaluate risk factors for biopsy site misidentification, postponement of surgery, and patient confidence in surgical site selection and to assess the near-miss rate for wrong-site surgeries.
Methods:
This was a prospective observational cohort study.
Results:
Near-miss wrong-site surgeries were detected and averted in 1.3% (3 of 239) of patients with biopsy site photographs. Risk factors for biopsy site misidentification by patients were 6 weeks or longer between biopsy and surgery (odds ratio [OR] 2.19, 95% confidence interval [CI] 1.12-4.27; P = .028) and patient inability to see biopsy site (OR 3.95, 95% CI 1.50-10.37; P = .002). Risk factors for physician misidentification were 6 or more weeks between biopsy and surgery (OR 3.68, 95% CI 1.40-9.66; P = .007) and biopsy specimens from multiple sites (OR 4.39, 95% CI 1.67-11.54; P = .003). Postponement of surgery was associated with absence of a biopsy site photograph (OR 12.5, 95% CI 2.79-62.21; P < .001). Patient confidence in surgical site identification was associated with the presence of a biopsy site photograph (OR 5.48, 95% CI 1.96-15.30; P = .001).
Limitations:
This was a single-site observational study.
Conclusion:
Biopsy site photography is associated with reduced rates of postponed surgeries and improved rates of patient confidence in surgical site selection. Risk factors for biopsy site misidentification should be considered before definitive treatment.
