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The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
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Pyrene-based heparin sensors in competitive aqueous media - the role of self-assembled multivalency (SAMul)
1Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK. david.smith@york.ac.uk.
Abstract:
Amine-functionalised pyrene derivatives are reported and their ability to detect heparin via a fluorescent response determined - different responses are observed dependent on whether self-assembled multivalent binding between sensor and analyte takes place, and ratiometric heparin sensors which can detect this surgically-relevant polyanion in competitive media are reported.

