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Updated: Mar 26, 2026
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Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
Published on: March 9, 2018
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Technologies for Clinical Diagnosis Using Expired Human Breath Analysis
Thalakkotur Lazar Mathew1, Prabhahari Pownraj2, Sukhananazerin Abdulla3
1Nanosensor Laboratory, PSG Institute of Advanced Studies, Coimbatore641 004, India. tlazarmathew@gmail.com.
Diagnostics (Basel, Switzerland)
|February 9, 2016
Summary
Exhaled breath analysis offers a noninvasive method for detecting health and disease biomarkers. This review covers technologies, critical biomarkers, and nanotechnology applications in breath analysis.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Medical Diagnostics
Background:
- Exhaled breath analysis provides a noninvasive, rapid, and cost-effective approach for health and disease monitoring.
- It enables the detection of numerous volatile organic compounds (VOCs) indicative of physiological states.
- Advancements in analytical techniques are crucial for accurate and sensitive breath diagnostics.
Purpose of the Study:
- To review current technologies for exhaled breath analysis.
- To highlight critical biomarkers in human breath and their implications.
- To discuss the integration of nanotechnology in breath analysis for medical monitoring.
Main Methods:
- Spectrometry
- Gas Chromatography
- Spectroscopy
- Nanotechnology-based sensors
Main Results:
- Exhaled breath analysis identifies various compounds related to health and disease.
- Key biomarkers and their physiological effects are discussed.
- Nanotechnology-based techniques show promise for enhanced breath analysis.
Conclusions:
- Exhaled breath analysis is a valuable tool for noninvasive diagnostics.
- Further development of nanotechnology-based sensors can improve medical monitoring.
- This field offers significant potential for early disease detection and management.
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