[Indirect immunofluorescence in bladder tumors]

Fourty three patients with transient-cell bladder carcinoma had complete investigations performed for determining maximal number of parameters characterizing the tumors--gross appearance (mode of growth and dissemination, size, multiplicity, localization, infiltration stage, differentiation grade), cytophotometric data (ploidy and proportion of cells in S-phase). In direct immunofluorescence was applied as diagnostic test for assessing the immune response of the organism to its own tumor. Information on the immune response was also obtained by determination of the IgA and IgG levels in the patients' sera. A clearcut correlation was found between tumor malignancy parameters and immunofluorescence intensity. Inferences were made on the value of indirect immunofluorescence for the diagnosis, choice of treatment and prognosis of bladder tumors. The trends in the further searches in the immunology of these tumors are outlined.