Early development of comorbidity between symptoms of attention-deficit/hyperactivity disorder (ADHD) and oppositional

Elizabeth A Harvey1, Rosanna P Breaux1, Claudia I Lugo-Candelas1

  • 1Department of Psychological and Brain Sciences, University of Massachusetts Amherst.

Insights

Attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) frequently co-occur in preschoolers. ADHD symptoms predict later defiance, while family history influences both ADHD and ODD development.

Area of Science:

  • Child Psychology
  • Developmental Psychology
  • Psychopathology

Background:

  • Attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are common childhood disorders with frequent comorbidity.
  • Understanding the developmental pathways of this comorbidity during the critical preschool years is essential.

Purpose of the Study:

  • To investigate the developmental interplay between ADHD and ODD symptoms in preschoolers.
  • To test a cross-lagged model integrating the developmental precursor and correlated risk factors models.

Main Methods:

  • Longitudinal study of 199 preschoolers (ages 3-6) with behavior problems.
  • Annual parent reports of ADHD and ODD symptoms.
  • Family history interviews for ADHD and ODD/CD symptoms at age 3.

Main Results:

  • ADHD symptoms at earlier ages predicted later argumentative/defiant symptoms (developmental precursor model).
  • Family history of ADHD and ODD/CD uniquely predicted child ADHD and anger/irritability symptoms (correlated risk factors model).
  • Different models explained distinct aspects of ADHD-ODD comorbidity.

Conclusions:

  • The correlated risk factors model best explains comorbidity between ADHD and anger/irritability symptoms.
  • The developmental precursor model better explains comorbidity between ADHD and argumentative/defiance symptoms.
  • These findings offer insights into the complex developmental trajectories of childhood behavioral disorders.

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