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Pediatric Headache and Epilepsy Comorbidity in the Pragmatic Clinical Setting

Antigone S Papavasiliou1, Marianna Bregianni1, Irene Nikaina1

  • 1Department of Pediatric Neurology, Pendeli Children's Hospital, Athens, Greece.

Neuropediatrics
|February 9, 2016
PubMed

Insights

Migraine and epilepsy co-occurred infrequently in children, contrary to some literature. However, a family history of headaches was common in children with benign childhood epilepsy with centro-temporal spikes and childhood absence epilepsy.

Area of Science:

  • Neurology
  • Pediatrics
  • Epileptology

Background:

  • Investigated the co-occurrence of headaches and epilepsy in pediatric populations.
  • Collected data from headache and epilepsy clinics using structured interviews.

Purpose of the Study:

  • To examine the co-occurrence of headaches and epilepsy in children.
  • To assess the family history of headaches in children with specific epilepsy syndromes.

Main Methods:

  • Evaluated 172 children from a headache clinic for epilepsy diagnoses.
  • Assessed 70 children from an epilepsy clinic for headache types and diagnoses.
  • Surveyed 149 parents of children with benign childhood epilepsy with centro-temporal spikes (BCECTS) and childhood absence epilepsy (CAE) regarding family history of headaches.

Main Results:

  • Only 1.7% of children in the headache clinic sample had epilepsy. Migraine and epilepsy co-occurred in 2.3% of migraine patients.
  • 11.4% of epilepsy patients reported headaches, but none had migraine.
  • 43% of patients with BCECTS or CAE had a family history of headache, with higher prevalence in first-degree relatives of BCECTS patients.

Conclusions:

  • Migraine and epilepsy co-occurred infrequently in these selected pediatric samples, contrasting with some existing literature.
  • A significant family history of headaches was observed in children with BCECTS and CAE.
Abstract

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