[Clinical syndromes with liver and kidney involvement in children and adults]

Multiple pathogenetic mechanisms can lead to dysfunctions or malformations of the liver and kidneys in children and adults. The association of renal and hepatic abnormalities can be found in different congenital malformation syndromes. Hereditary metabolic disorders are capable of alternating liver and kidney function. Immunologic, toxic and septic diseases may damage both organ systems. In patients with liver cirrhosis, both glomerular and tubular dysfunctions can be observed. In the course of liver transplantations, an increased rate of renal dysfunction was observed. This survey summarizes the main clinical syndromes of renal involvement associated with liver disease.