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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Related Experiment Video

Updated: Mar 26, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach
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Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach

Published on: May 23, 2025

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Hand Transplantation Versus Hand Prosthetics: Pros and Cons.

S Salminger1, A D Roche2, A Sturma3

  • 1Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria ; Christian Doppler Laboratory for Restoration of Extremity Function, Medical University of Vienna, Vienna, Austria.

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|February 9, 2016
PubMed
Summary
This summary is machine-generated.

Restoring function for upper limb amputees involves hand transplantation or prosthetics. The best option depends on amputation level and extent, each with unique benefits and drawbacks.

Keywords:
Hand amputationHand prosthesisHand transplantationReconstructionUpper extremity

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Area of Science:

  • Regenerative Medicine
  • Biomedical Engineering
  • Orthopedic Surgery

Background:

  • Upper limb amputation presents challenges in restoring function.
  • Composite tissue transplantation and advanced prosthetics offer new solutions.
  • Patient selection is crucial for optimal outcomes.

Approach:

  • Review of current literature on hand transplantation and prosthetic options.
  • Analysis of advantages and disadvantages for each treatment modality.
  • Consideration of amputation level and extent (unilateral/bilateral).

Key Points:

  • Hand transplantation can restore comprehensive function but carries risks and is controversial.
  • Prosthetic limb replacement is standard but has limitations in function, sensation, and usage.
  • Treatment choice is highly dependent on individual amputation characteristics.

Conclusions:

  • Both hand transplantation and prosthetics have roles in upper limb reconstruction.
  • Careful evaluation of patient-specific factors is essential for decision-making.
  • Further research may refine indications and improve outcomes for both approaches.