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Updated: Mar 26, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
In adult smokers unwilling or unable to quit, does changing from tobacco cigarettes to electronic cigarettes decrease
Jennifer Brown1, Brandon Brown1, Peter Schwiebert1
1Family Medicine Residency Program, Department of Family & Preventive Medicine, University of Oklahoma College of Medicine, 900 NE 10 St., Oklahoma City, OK 73104.
Abstract:
Data from a randomized controlled trial and systematic review support the claim that switching from tobacco cigarettes to electronic cigarettes (e-cigarettes) can reduce the short-term negative health effects of smoking. In adult smokers unwilling or unable to quit, exhaled carbon monoxide levels, total number of cigarettes smoked, and exposure to nitrosamine chemicals were reduced within a 12-month period. While the electronic cigarette industry remains largely unregulated thus far, these studies provide encouraging hope in the uphill battle toward helping patients make informed and healthy choices.
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