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Surgical anatomy of the sciatic nerve: A meta-analysis
Krzysztof A Tomaszewski1,2, Matthew J Graves3,4, Brandon Michael Henry3,4
1International Evidence-Based Anatomy Working Group, Krakow, Poland. krtomaszewski@gmail.com.
Summary
Sciatic nerve variations occur in nearly 15% of individuals, impacting its relationship with the piriformis muscle. Understanding these anatomical differences is crucial for preventing iatrogenic nerve injuries during surgical procedures.
Area of Science:
- Anatomy
- Orthopedics
- Surgical Anatomy
Background:
- The sciatic nerve's anatomical course relative to the piriformis muscle exhibits significant variation.
- Knowledge of these variations is critical for preventing iatrogenic nerve injuries during pelvic and gluteal region procedures.
Purpose of the Study:
- To systematically review and meta-analyze the prevalence of sciatic nerve anatomical variations.
- To provide morphometric data on sciatic nerve variations in relation to the piriformis muscle.
Main Methods:
- A comprehensive electronic database search was conducted to identify relevant studies.
- Data from 45 studies (7068 lower limbs) were extracted and pooled for meta-analysis.
Main Results:
- The typical sciatic nerve variation (Type A) had a pooled prevalence of 85.2%.
- Anatomical variations (e.g., Type B, where the nerve bifurcates) were observed in approximately 15% of cases.
- Pooled mean sciatic nerve width was 15.55 mm; mean bifurcation distance from the popliteal fossa was 65.43 mm.
Conclusions:
- Sciatic nerve anatomical variations are common, occurring in nearly 15% of the population.
- Preoperative assessment of sciatic nerve variants is recommended for procedures in the pelvic and gluteal regions.
- Awareness of these variations can significantly reduce the risk of iatrogenic sciatic nerve injury.

