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Associations between nutrition and cataract.

A Taylor

    Nutrition Reviews
    |August 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Delaying cataract onset by ten years could halve surgical needs. Specific nutrients like carotenoids and vitamins may protect against age-related vision impairment, offering hope for preventing blindness.

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    Area of Science:

    • Ophthalmology and nutritional science.
    • Biochemistry and molecular biology of lens aging.

    Background:

    • Cataract, or lens opacification, causes blindness in 50 million worldwide.
    • Annual US cataract surgeries exceed 541,000, costing over $3.8 billion.
    • Cataract prevalence increases significantly with age, affecting 18% of 65-75 year olds and 46% of 75-85 year olds.

    Purpose of the Study:

    • To explore the etiology of cataracts and identify potential preventative strategies.
    • To investigate the role of specific nutrients and caloric restriction in delaying cataract development.

    Main Methods:

    • Review of epidemiological data linking nutrient plasma levels to cataract incidence.
    • Examination of biochemical evidence for antioxidant and metabolic roles of nutrients in the lens.

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  • Discussion of current research into caloric restriction's effects on cataractogenesis.

    • Main Results:

    • Elevated plasma levels of carotenoids, ascorbate, tocopherol, and taurine are associated with reduced cataract incidence.
    • These nutrients demonstrate potential to delay photooxidative damage to lens proteins.
    • Caloric restriction is identified as a promising area for further research in cataract prevention.

    Conclusions:

    • Nutritional interventions and lifestyle modifications like caloric restriction may offer viable strategies for delaying cataract onset.
    • Further research into nutrient metabolism and oxidative stress in the lens is warranted.
    • Delaying cataract development holds significant potential for reducing global blindness and healthcare costs.