Related Experiment Video
Updated: Mar 26, 2026

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities
Published on: December 25, 2015
Application of response surface methodology to optimize the operational parameters for enhanced removal efficiency of
Anjali Barwal1, Rubina Chaudhary2
1School of Energy and Environmental Studies, Faculty of Engineering Sciences, Devi Ahilya University, Takshashila Campus, Khandwa Road, Indore, Madhya Pradesh, 452001, India.
Abstract:
An attempt of response surface methodology (RSM) has been made for more effective utilization and optimization for considerable reduction of operational conditions such as reaction time, aeration time, energy consumption, etc. for municipal wastewater treatment process using moving bed biofilm reactor (MBBR). A mathematical-statistical model was developed for the second-order response surface through the fit of a polynomial function and a central composite design (CCD) in the form of a full factorial design. CCD was employed to assess the interactive effects of the three main independent operational parameters, including biocarrier filling rate (0-70 %), aeration rate (0.21-0.42 m(3) h(-1)), and reactor run time (1-15 days), on the removal efficiency of chemical oxygen demand (COD), biochemical oxygen demand (BOD), and total Kjeldahl nitrogen (TKN). Analysis of variance expressed a high coefficient of determination (R (2) = 0.84-0.95), thereby indicating that the model is significant. Using a desirability function for the highest COD (93 %), BOD (96 %), and TKN (69 %) removal, the optimum carrier filling rate, aeration rate, and reactor run time were identified to be 40 %, 0.21 m(3) h(-1), and 7 days, respectively. It shows that RSM can be a suitable method to optimize the operational parameters of MBBR with enhanced removal efficiency and less power consumption.
More Related Videos
11:47Evaluation of the Efficacy of Organic Peroxyacids for Eradicating Dairy Biofilms Using an Approach Combining Static and Dynamic Methods
Published on: December 9, 2022
06:24Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
Related Concept Videos
Bioreactor Design and Operational System
Bioreactor Controls-II
Methods of Medium Optimization
Designing Growth Media for Bioreactors
Bioreactor Controls-I
Response Surface Methodology
The process of RSM involves several key steps: