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Biologic response modifiers in cancer therapy: a review

Texas Medicine
|November 1, 1989
PubMed

Insights

Biologic response modifiers are emerging as a fourth pillar of cancer therapy. This review covers key research areas like cytokines, growth factors, and immunotherapy, highlighting their therapeutic potential in oncology.

Area of Science:

  • Oncology
  • Immunology
  • Biotechnology

Background:

  • Biologic response modifiers represent a significant advancement in cancer treatment.
  • These agents are poised to become a major therapeutic modality alongside surgery, radiation, and chemotherapy.

Purpose of the Study:

  • To review prominent areas of clinical research in biologic response modifiers.
  • To summarize the obtained results from these investigations.

Main Methods:

  • Review of clinical research findings.
  • Analysis of data on cytokines (interferons, interleukins), growth factors, monoclonal antibodies, adoptive immunotherapy, and tumor vaccines.

Main Results:

  • Biologic response modifiers have demonstrated significant therapeutic potential.
  • Key areas of research show promising results in various cancer types.

Conclusions:

  • Biologic response modifiers are expanding the therapeutic options in medical oncology.
  • These innovative approaches are likely to be integrated as a standard fourth-line cancer treatment.

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