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Updated: Aug 18, 2026

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
Published on: May 18, 2020
Abstract:
Breast reconstruction has been playing an increasing role in breast cancer therapy at The University of Texas M. D. Anderson Cancer Center. Our goal is not only to correct cosmetic deformity but also to allow mastectomy patients to wear normal clothing and function as normally as possible in society. Reconstruction is now available to most women who request it. The most commonly used techniques, in our institution, are tissue expansion, use of the latissimus dorsi flap, and use of the transverse rectus abdominis musculocutaneous (TRAM) flap. Each has advantages and disadvantages, with the choice of method depending on individual circumstances. In most cases, successful breast reconstruction can be achieved.
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