Chlorambucil-Induced Radiation Recall Dermatitis.

Area of Science:

• Oncology
• Hematology
• Radiation Oncology

Background:

• Low-grade non-Hodgkin lymphoma is a type of cancer affecting white blood cells.
• Treatment protocols often involve combination chemotherapy and radiation therapy.

Observation:

• A 65-year-old female patient was diagnosed with low-grade non-Hodgkin lymphoma.
• The patient received six cycles of cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone (CHOP).
• She subsequently underwent three cycles of fludarabine and mitoxantrone.

Findings:

• Ten months post-chemotherapy, the patient received radiotherapy to the left groin.
• The radiation dose was 50 Gy delivered in 25 fractions over 5 weeks.
• The treatment course was completed without any reported complications.

Implications:

• This case highlights a feasible treatment approach for low-grade non-Hodgkin lymphoma.
• Successful management with combined modality treatment suggests potential for favorable outcomes.
• Further research may explore optimal sequencing and long-term efficacy of such regimens.