Pulmonary Nocardiosis in a Multiple Myeloma Patient Treated with Proteasome Inhibitors

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Nikolai P Mendonca1, Deepak K Kadayakkara1, Inga C Forde1

  • 1Department of Internal Medicine, Bridgeport Hospital - Yale New Haven Health, Bridgeport, CT, USA.

The American Journal of Case Reports
|February 11, 2016
PubMed
Abstract

Insights

Newer multiple myeloma treatments like Carfilzomib may increase Nocardia infection risk, especially with lymphopenia. Early suspicion and treatment are crucial for patients undergoing novel chemotherapy.

Area of Science:

  • Oncology
  • Infectious Diseases

Background:

  • Proteasome inhibitors (e.g., Bortezomib) for multiple myeloma are linked to opportunistic infections like Nocardia, particularly with lymphopenia.
  • The association of Nocardia infections with newer agents like Carfilzomib remains unclear.

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