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Updated: Mar 26, 2026
The α-test: Rapid Cell-free CD4 Enumeration Using Whole Saliva
Published on: May 16, 2012
THE EFFECT OF CD4 COUNT LEVEL ON THE MIDDLE EAR DYNAMICS OF HIV INFECTED PATIENTS
Background:
HIV infection, a multi systemic disease has been identified as one of the causes of hearing loss in man.
Objectives:
To compare the effect of HIV infection on the middle ear dynamics of HIV infected and non-HIV infected individuals using tympanometry.
Design:
A prospective cross sectional study.
Setting:
HIV Clinic at University of Benin Teaching Hospital (UBTH) in 2010.
Subjects:
Tympanometry was done on adults (18-45 year old) patients with confirmed retroviral disease (RVD) infection and confirmed non-HIV infected adults (18-45 year old) as the control group. All the patients certified the inclusion and exclusion criteria.
Main Outcome Measures:
More women were found with HIV infection than men at a ratio of 1:3.7(men = 21% and females = 79%). There was preponderance of type "B" tympanogram among HIV-infected individuals.
Result:
There was a significant correlation between CD4 cell count and type "B" tympanogram (P = 0.03). The CD4 cell count measured severity of HIV infection while the type "B" tympanogram detected middle ear effusion.
Conclusions:
Middle ear effusion is the genesis of middle ear pathology in HIV infected population.
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