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Updated: Sep 27, 2026
Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
Published on: April 3, 2015
[Vascular replacement--a critical evaluation of status]
M Kadletz1, A Rokitansky, E Wolner
1Aus der II. Chirurgischen Universitätsklinik Wien.
The beginning of angioplasty dates back to the turn of this century. Two lines of research were pursued over the past 40 years, organic and synthetic replacements of vessels. Autologous replacement, using an endogenous extremity vein, proved to be the most favourable variant. It was found to be not applicable to about 20 per cent of all patients, so that allogenic, semixenogenic or synthetic substitutes were required. Synthetic replacement was found to be characterised by a high rate of longtime closure, attributable to good biocompatibility of synthetic prostheses and low thrombogenic property of their inner surfaces. Endothelialisation of the prosthesis would be a possibility to improve the rate of success in bypass vascular surgery.
The beginning of angioplasty dates back to the turn of this century. Two lines of research were pursued over the past 40 years, organic and synthetic replacements of vessels. Autologous replacement, using an endogenous extremity vein, proved to be the most favourable variant. It was found to be not applicable to about 20 per cent of all patients, so that allogenic, semixenogenic or synthetic substitutes were required. Synthetic replacement was found to be characterised by a high rate of longtime closure, attributable to good biocompatibility of synthetic prostheses and low thrombogenic property of their inner surfaces. Endothelialisation of the prosthesis would be a possibility to improve the rate of success in bypass vascular surgery.
