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Updated: Mar 26, 2026

Horizontal Hippocampal Slices of the Mouse Brain
Published on: September 22, 2020
Anterior hippocampus: the anatomy of perception, imagination and episodic memory
Peter Zeidman1, Eleanor A Maguire1
1Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Abstract:
The brain creates a model of the world around us. We can use this representation to perceive and comprehend what we see at any given moment, but also to vividly re-experience scenes from our past and imagine future (or even fanciful) scenarios. Recent work has shown that these cognitive functions--perception, imagination and recall of scenes and events--all engage the anterior hippocampus. In this Opinion article, we capitalize on new findings from functional neuroimaging to propose a model that links high-level cognitive functions to specific structures within the anterior hippocampus.
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