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Updated: Mar 26, 2026
Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Spontaneous cerebrospinal fluid leak at the clivus
Krzysztof Oleś1, Jacek Składzien2, Marek Betlej3
1Department of Otolaryngology, Jagiellonian University, Medical College, Krakow, Poland; Department of Otolaryngology and Reconstructive Surgery, Institute of Oncology Gliwice Branch, The Maria Sklodowska-Curie Memorial Cancer Center, Gliwice, Poland.
Abstract:
We present a case report of a 60-year-old woman with a spontaneous cerebrospinal fluid leak at the clivus, obesity and no history of trauma. Follow-up imaging scans confirmed enlargement of the defect within the posterior clival framework to the size of 16 × 9 × 4 mm with a suspected meningocerebral hernia. The surgeons used the "two nostrils - four hands" endoscopic operating technique. The patient reported a history of cerebrospinal fluid leaks lasting for 3 years, with increasingly shorter leak-free periods and an increasing incidence of inflammatory complications. The patient recovered without complications, and she was discharged 14 days after the surgery. Good local outcome and improved patient condition were achieved postoperatively.
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