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Real-Time Void Spot Assay
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Voiding Dysfunction in Multiple Sclerosis.

Anton Wintner1, Michelle M Kim1, Seth K Bechis1

  • 1Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Seminars in Neurology
|February 12, 2016
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis (MS) frequently causes debilitating urinary problems, impacting bladder and sphincter function. Treatment aims to protect kidneys, prevent infections, and maintain continence through various interventions.

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Area of Science:

  • Neurology
  • Urology

Background:

  • Voiding dysfunction is a common and debilitating consequence of multiple sclerosis (MS).
  • Urinary symptoms affect 30% of patients, even with mild MS.
  • MS impacts central nervous system regulation of voiding, leading to diverse urinary issues.

Purpose of the Study:

  • To classify the effects of MS on bladder and urethral sphincter function during urine storage and emptying.
  • To outline therapeutic strategies targeting specific bladder and sphincter abnormalities.
  • To emphasize the primary goals of managing MS-related voiding dysfunction.

Main Methods:

  • Classification of voiding dysfunction based on bladder and urethral sphincter function during storage and emptying.
  • Targeted therapy based on identified bladder and sphincter abnormalities.
  • Interventions ranging from behavioral modification to reconstructive surgery.

Main Results:

  • MS can lead to a wide spectrum of urinary symptoms and urologic complications.
  • Therapy is tailored to specific bladder and sphincter dysfunctions.
  • Successful management involves preventing kidney injury, reducing infections, and maintaining continence.

Conclusions:

  • Voiding dysfunction is a significant complication of MS, varying with disease severity.
  • Comprehensive management strategies are crucial for improving quality of life and preventing serious urologic issues.
  • Interdisciplinary approaches are key to addressing the complex urologic needs of MS patients.