Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current practice patterns for cleaning tonometry tips and diagnostic/laser lenses.

Journal of cataract and refractive surgery·2026
Same author

Prevention of endophthalmitis with cataract surgery<i>: where are we now 20 years after the ESCRS Study?</i>

The British journal of ophthalmology·2026
Same author

Implementing Shared Decision-Making in Haemophilia Care: Best Practice Recommendations From a Western European Multi-Stakeholder Delphi Process.

Haemophilia : the official journal of the World Federation of Hemophilia·2026
Same author

LASIK for Hyperopia: A Report by the American Academy of Ophthalmology.

Ophthalmology·2026
Same author

Medical and surgical interventions for neurotrophic keratopathy.

The Cochrane database of systematic reviews·2025
Same author

Antibiotic prophylaxis for corneal abrasion.

The Cochrane database of systematic reviews·2025

Related Experiment Video

Updated: Mar 26, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

10.9K

Conjunctival autograft for pterygium.

Elizabeth Clearfield1, Valliammai Muthappan, Xue Wang

  • 1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Room 6014, Baltimore, Maryland, USA, 21205.

The Cochrane Database of Systematic Reviews
|February 12, 2016
PubMed
Summary

Conjunctival autograft surgery shows a lower pterygium recurrence rate at six months compared to amniotic membrane grafts, especially for recurrent cases. Further research is needed on visual outcomes and costs.

More Related Videos

An &#8220;All-laser&#8221; Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

10.0K
Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
09:03

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation

Published on: November 17, 2014

10.3K

Related Experiment Videos

Last Updated: Mar 26, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

10.9K
An &#8220;All-laser&#8221; Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

10.0K
Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
09:03

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation

Published on: November 17, 2014

10.3K

Area of Science:

  • Ophthalmology
  • Surgical Innovation

Background:

  • Pterygium is a wing-shaped conjunctival growth that can impair vision and cause discomfort.
  • Surgical excision is the primary treatment, but recurrence rates can be high with simple techniques.
  • Grafting procedures, including conjunctival autograft and amniotic membrane graft, aim to reduce recurrence.

Purpose of the Study:

  • To compare the safety and effectiveness of conjunctival autograft versus amniotic membrane graft for pterygium.
  • To evaluate the impact of mitomycin C (MMC) on surgical outcomes.
  • To assess the comparative costs of these surgical procedures.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials.
  • Searched multiple databases including CENTRAL, MEDLINE, EMBASE, PubMed, LILACS, mRCT, ClinicalTrials.gov, and WHO ICTRP.
  • Included trials comparing conjunctival autograft with amniotic membrane graft for primary or recurrent pterygium.

Main Results:

  • Twenty studies involving 1947 eyes were analyzed.
  • Conjunctival autograft demonstrated a lower risk of pterygium recurrence at 6 months (Risk Ratio 0.53; 95% CI 0.33 to 0.85).
  • Recurrent pterygia cases showed a significantly lower recurrence risk with conjunctival autograft (Risk Ratio 0.45; 95% CI 0.21 to 0.99).

Conclusions:

  • Conjunctival autograft is associated with a lower pterygium recurrence rate at six months post-surgery compared to amniotic membrane transplant.
  • This benefit is particularly noted in patients with recurrent pterygia.
  • Further investigation is required for visual acuity, quality of life, and cost-effectiveness outcomes.