HISTOPLASMOSIS MYOSITIS: A CASE REPORT AND LITERATURE REVIEW
Abstract:
Disseminated histoplasmosis is an AIDS-defining illness that can affect multiple organ systems. Myositis due to histoplasmosis is rare in HIV infected patients. We report here an HIV-infected patient who presented with myositis caused by Histoplasma capsulatum. Her HIV was under poor control and her CD4 cell count was only 11 cells/mm3. She responded well to treatment but later succumbed to another opportunistic infection. The literature on disseminated histoplasmosis is reviewed.
Insights
Disseminated histoplasmosis, an AIDS-defining illness, can cause myositis in patients with advanced HIV infection. This case highlights a rare presentation of Histoplasma capsulatum-induced myositis in an immunocompromised individual.
Area of Science:
- Infectious Diseases
- Immunology
- Myology
Background:
- Disseminated histoplasmosis is a significant opportunistic infection in individuals with advanced Human Immunodeficiency Virus (HIV) infection, often defining Acquired Immunodeficiency Syndrome (AIDS).
- Myositis, or inflammation of the muscles, is an uncommon manifestation of disseminated histoplasmosis, particularly in the context of HIV/AIDS.
- The clinical presentation and management of rare opportunistic infections in immunocompromised patients remain critical areas of study.
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