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Cryptococcemia in primary HIV infection.

Victor Au Yeung1, Rula Azzam1, Claire Dendle2

  • 1Monash Infectious Diseases, Monash Health, Monash University, Australia.

International Journal of STD & AIDS
|February 13, 2016
PubMed
Summary
This summary is machine-generated.

Cryptoccemia is rare in early HIV infection, but this case shows it can occur. Clinicians should consider cryptococcosis and other opportunistic infections in patients with primary HIV infection.

Keywords:
CryptococcemiaHIV seroconversioncryptococcusprimary HIV infection

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Area of Science:

  • Infectious Diseases
  • Virology
  • Immunology

Background:

  • Primary HIV infection is typically characterized by low rates of opportunistic infections.
  • Opportunistic infections usually manifest later in the disease course as immune deficiency progresses.

Observation:

  • A case of cryptococcemia was observed during the primary stage of human immunodeficiency virus (HIV) infection.
  • This presentation is unusual, as cryptococcosis is seldom reported in this early phase of HIV.

Findings:

  • Cryptococcemia occurred in the setting of primary HIV infection, a previously unreported occurrence.
  • The findings suggest that opportunistic infections can manifest earlier than commonly believed in HIV infection.

Implications:

  • Clinicians must maintain a high index of suspicion for opportunistic infections, including cryptococcosis, during primary HIV infection.
  • Early recognition and management of opportunistic infections are crucial for improving outcomes in early HIV disease.
  • This case underscores the variability in clinical presentation during primary HIV infection.