Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pyrolytic hydrocarbon growth from cyclopentadiene.

The journal of physical chemistry. A·2010

Same author

In(III)-catalyzed tandem reaction of chromone-derived Morita-Baylis-Hillman alcohols with amines.

Organic & biomolecular chemistry·2010

Same author

Regression-based multi-trait QTL mapping using a structural equation model.

Statistical applications in genetics and molecular biology·2010

Same author

Elevated expression of APE1/Ref-1 and its regulation on IL-6 and IL-8 in bone marrow stromal cells of multiple myeloma.

Clinical lymphoma, myeloma & leukemia·2010

Same author

Accelerated aging of intervertebral discs in a mouse model of progeria.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2010

Same author

The synthesis of a multiblock osteotropic polyrotaxane by copper(I)-catalyzed huisgen 1,3-dipolar cycloaddition.

Macromolecular bioscience·2010

Same journal

A critical commentary on CrossFit Research® with coach insights on training monitoring and physical assessment.

The Journal of sports medicine and physical fitness·2026

Same journal

Age-related differences during stop-ball small-sided games in youth soccer.

The Journal of sports medicine and physical fitness·2026

Same journal

Dynamic multi and single joint strength and vertical jump performance in amateur athletes who have returned to sport following anterior cruciate ligament reconstruction.

The Journal of sports medicine and physical fitness·2026

Same journal

Fluid loss during tennis matches is associated with reduced muscle strength in sport-specific limbs.

The Journal of sports medicine and physical fitness·2026

Same journal

Implementing ECG screening in Florida (USA): a wishful thinking or a valid opportunity?

The Journal of sports medicine and physical fitness·2026

Same journal

The ACC opposition to legislative ECG screening mandates for competitive athletes.

The Journal of sports medicine and physical fitness·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 25, 2026

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

Identification of human exercise-induced physiological function changes based on bioinformatics analysis.

Liquan Yin¹, Fei Cai², Dong Wang³

¹Rehabilitation Medicine Department, China-Japan Union Hospital of Jilin University, Changchun, China.

The Journal of Sports Medicine and Physical Fitness

|February 13, 2016

Summary

This summary is machine-generated.

Exercise training significantly impacts physiological functions, altering gene expression and pathways involved in blood vessel development and cell migration. This study identifies key genes and functions affected by physical activity.

More Related Videos

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Related Experiment Videos

Last Updated: Mar 25, 2026

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Area of Science:

Exercise physiology
Molecular biology
Genomics

Background:

Exercise training induces significant physiological changes.
Understanding these changes at a molecular level is crucial.

Purpose of the Study:

To identify physiological functions significantly affected by exercise training.
To explore the molecular mechanisms underlying these changes.

Main Methods:

Analysis of the GSE53598 microarray dataset.
Identification of differentially expressed genes (DEGs) in muscle biopsies pre- and post-exercise.
Construction of protein-protein interaction (PPI) networks and functional enrichment analysis.

Main Results:

Identified 420 up-regulated and 420 down-regulated DEGs.
Key DEGs in the PPI network included E2F transcription factor 6 and caveolin 1.
Significant changes observed in functions related to blood vessel development and cell migration.

Conclusions:

Exercise training impacts blood vessel development and cell migration.
Negative regulation of gene expression and metabolic processes are also significantly affected.
These functions are likely closely associated with the physiological adaptations to exercise.